THE DEFINITIVE GUIDE TO BOSENTAN

six The phosphodiesterase-5 inhibitor sildenafil is accredited for PAH in FC I–IV inside the United states of america and FC II–III in Europe. Endothelin receptor antagonists (ERAs) which include bosentan, sitaxentan and ambrisentan are oral therapies licensed for use in PAH. As no oral agent has proven superiority there remains debate concerni